Recombinant Human SEC62 Protein, MYC/DDK-tagged

• Cat.No.: SEC62-607H
• Product Overview: Recombinant human SEC62 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 45.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SEC62 homolog, preprotein translocation factor[ Homo sapiens ]
• Official Symbol: SEC62
• Synonyms: Dtrp1; HTP1; TLOC1; TP-1
• Gene ID: 7095
• mRNA Refseq: NM_003262.3
• Protein Refseq: NP_003253.1
• MIM: 602173
• UniProt ID: Q99442