Recombinant Human SELPLG Protein, hIgG/His-tagged
Cat.No. : | SELPLG-03H |
Product Overview : | Recombinant human PSGL-1 (496aa), fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | hIgG/His |
Form : | Liquid |
Molecular Mass : | 53.4 kDa |
Protein length : | 42-295 |
AA Sequence : | |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | >90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/mL (determinedby Absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | SELPLG selectin P ligand [ Homo sapiens (human) ] |
Official Symbol : | SELPLG |
Synonyms : | SELPLG; selectin P ligand; CLA; CD162; PSGL1; PSGL-1; P-selectin glycoprotein ligand 1; cutaneous lymphocyte-associated associated antigen |
Gene ID : | 6404 |
mRNA Refseq : | NM_003006 |
Protein Refseq : | NP_002997 |
MIM : | 600738 |
UniProt ID : | Q14242 |
Products Types
◆ Recombinant Protein | ||
SELPLG-834H | Recombinant Human SELPLG protein(Met1-Val295), His&hFc-tagged | +Inquiry |
SELPLG-129H | Recombinant Human SELPLG Protein, C-His-tagged | +Inquiry |
SELPLG-242H | Active Recombinant Human SELPLG Protein, Fc-tagged | +Inquiry |
SELPLG-531H | Recombinant Human SELPLG Protein, Fc-tagged | +Inquiry |
SELPLG-2049H | Recombinant Human SELPLG Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SELPLG-1089HCL | Recombinant Human SELPLG cell lysate | +Inquiry |
SELPLG-001MCL | Recombinant Mouse SELPLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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