Recombinant Human SENP1, His-tagged
Cat.No. : | SENP1-687H |
Product Overview : | Recombinant, human SENP1 consisting of aminoacids 419-643 fused at the N-terminus to a His Tag and expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SENP1-687H |
Description : | SENP1, a nuclear SUMO protease, regulatesandrogen receptor transactivation by targeting histone deacetylase 1 andc-Jun activity through deSUMOylation of p300. Recent data shows SENP1 isrequired for HIF-dependent transcription during embryogenesis and in responseto hypoxia. The protease is useful in the study of SENP1 endopeptidase andisopeptidase activity and for inhibitor screening. |
Source : | E. Coli |
Formulation : | In 50 mM HEPES, 5% glycerol pH 7.4. |
Biologicalactivity : | EC50:≥1.42 nM as determined using proSUMO-1 substrate in an endopeptidase assay. |
Purity : | ≥90% by SDS-PAGE |
Applications : | Enzyme-linkedImmunoabsorbent Assay; Western Blot (Recombinant protein); AntibodyProduction;ProteinArray |
Storagebuffer : | 50mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Storage : | ≤-70°C |
Gene Name : | SENP1SUMO1/sentrin specific peptidase 1 [ Homo sapiens ] |
Official Symbol : | SENP1 |
Synonyms : | SENP1; SUMO1/sentrin specific peptidase 1; SuPr-2;sentrin-specific protease 1; SUMO1/sentrin specific protease 1;sentrin/SUMO-specific protease SENP1 |
Gene ID : | 29843 |
mRNA Refseq : | NM_014554 |
Protein Refseq : | NP_055369 |
MIM : | 612157 |
UniProt ID : | Q9P0U3 |
Chromosome Location : | 12q13.1 |
Pathway : | Androgen Receptor Signaling Pathway; Regulationof Androgen receptor activity |
Function : | cysteine-typepeptidase activity; endopeptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
SENP1-8013M | Recombinant Mouse SENP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SENP1-686H | Active Recombinant Human SENP1, GST-tagged | +Inquiry |
SENP1-14878M | Recombinant Mouse SENP1 Protein | +Inquiry |
SENP1-2576H | Recombinant Human SENP1, His-tagged | +Inquiry |
SENP1-180H | Recombinant Human SENP1, His-tagged | +Inquiry |
◆ Lysates | ||
SENP1-1975HCL | Recombinant Human SENP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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