Active Recombinant Human SENP2 Protein, His tagged

• Cat.No.: SENP2-29695TH
• Product Overview: Recombinant SENP2 (360-end) was expressed in E. coli cells using an N-terminal His tag. The SENP2 gene accession number is NM_021627.

Specification

• Species: Human
• Source: E. coli
• Tag: His
• Protein Length: 360-589 aa
• Description: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM sodium phosphate, pH 7.5, 300mM NaCl, 50-200mM imidazole, 0-0.1mM PMSF, 0.2-1.0mM DTT, 10-25% glycerol.
• Reference: 1. Chung, S.S. et al: Control of adipogenesis by the SUMO specific protease SENP2. Mol. Cell. Biol. 30:2135-2146, 2010. 2. Hang, J. & Dasso, M: Association of the human SUMO-1 protease SENP2 with the nuclear pore. J. Biol. Chem. 277 (22): 19961–6, 2002.

Gene Information

• Gene Name: SENP2 SUMO specific peptidase 2 [ Homo sapiens (human) ]
• Official Symbol: SENP2
• Synonyms: SENP2; SUMO specific peptidase 2; AXAM2; SMT3IP2; sentrin-specific protease 2; SMT3-specific isopeptidase 2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2; sentrin (SUMO1) specific peptidase 2; sentrin/SUMO-specific protease SENP2; EC 3.4.22.68
• Gene ID: 59343
• mRNA Refseq: NM_021627
• Protein Refseq: NP_067640
• MIM: 608261
• UniProt ID: Q9HC62