Recombinant Human SETD2 Protein, His-tagged
Cat.No. : | SETD2-023H |
Product Overview : | Recombinant Human SETD2 protein (1435-1711) with a N-terminal His-tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 33.7 kDa |
Protein length : | 1435-1711 |
Purity : | ≥95% estimated by SDS-PAGE |
Stability : | ≥ 9 months |
Storage : | -80 centigrade |
Storage Buffer : | 50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride and 20% glycerol |
Gene Name : | SETD2 SET domain containing 2, histone lysine methyltransferase [ Homo sapiens (human) ] |
Official Symbol : | SETD2 |
Synonyms : | SETD2; SET domain containing 2, histone lysine methyltransferase; LLS; HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP; histone-lysine N-methyltransferase SETD2; SET domain containing 2; huntingtin interacting protein 1; huntingtin yeast partner B; huntingtin-interacting protein B; lysine N-methyltransferase 3A; protein-lysine N-methyltransferase SETD2; EC 2.1.1.359 |
Gene ID : | 29072 |
mRNA Refseq : | NM_014159 |
Protein Refseq : | NP_054878 |
MIM : | 612778 |
UniProt ID : | Q9BYW2 |
Products Types
◆ Recombinant Protein | ||
SETD2-8067M | Recombinant Mouse SETD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SETD2-460H | Recombinant Human SET Domain Containing 2, GST-tagged | +Inquiry |
SETD2-116H | Recombinant Human SETD2 Protein, His-tagged | +Inquiry |
SETD2-189H | Recombinant Human SETD2 Protein, His-tagged | +Inquiry |
SETD2-69H | Active Recombinant Human SETD2, FLAG-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1864 | SETD2 Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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