Recombinant Human SETD6 protein, GST-tagged, Active


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Recombinant Human SETD6 protein, GST-tagged, Active

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Cat.No. : SETD6-200H
Product Overview : Recombinant Human SETD6 fused with GST tag at N-terminal was expressed in Insect cells.
Description : SET domain-containing protein 6 (SETD6) is a mono-methyltransferase that has been shown to methylate RelA of NF-kappa-B complex and thus attenuate NF-kappa-B transcription factor activity. In addition, it monomethylates the histone H2A variant H2AZ which is required for the maintenance of embryonic stem cell self-renewal.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 380 nmol/min/mg
Molecular Mass : 75 kDa
Purity : >80%
Applications : Methyltransferase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Figure :

Gene Name : SETD6 SET domain containing 6 [ Homo sapiens ]
Official Symbol : SETD6
Synonyms : SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6;
Gene ID : 79918
mRNA Refseq : NM_001160305
Protein Refseq : NP_001153777
UniProt ID : Q8TBK2
Chromosome Location : 16q21
Function : NF-kappaB binding; methyltransferase activity; protein binding; protein-lysine N-methyltransferase activity; transferase activity;

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