Recombinant Human SETD7 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | SETD7-1794H |
Product Overview : | SETD7 MS Standard C13 and N15-labeled recombinant protein (NP_085151) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 40.5 kDa |
AA Sequence : | MDSDDEMVEEAVEGHLDDDGLPHGF CTVTYSSTDRFEGNFVHGEKNGRGK FFFFDGSTLEGYYVDDALQGQGVYT YEDGGVLQGTYVDGELNGPAQEYDT DGRLIFKGQYKDNIRHGVCWIYYPD GGSLVGEVNEDGEMTGEKIAYVYPD ERTALYGKFIDGEMIEGKLATLMST EEGRPHFELMPGNSVYHFDKSTSSC ISTNALLPDPYESERVYVAESLISS AGEGLFSKVAVGPNTVMSFYNGVRI THQEVDSRDWALNGNTLSLDEETVI DVPEPYNHVSKYCASLGHKANHSFT PNCIYDMFVHPRFGPIKCIRTLRAV EADEELTVAYGYDHSPPGKSGPEAP EWYQVELKAFQATQQKTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | SETD7 SET domain containing 7, histone lysine methyltransferase [ Homo sapiens (human) ] |
Official Symbol : | SETD7 |
Synonyms : | SETD7; SET domain containing (lysine methyltransferase) 7; histone-lysine N-methyltransferase SETD7; KIAA1717; KMT7; SET7; SET7/9; Set9; H3-K4-HMTase SETD7; lysine N-methyltransferase 7; SET domain-containing protein 7; histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; SET9; FLJ21193; |
Gene ID : | 80854 |
mRNA Refseq : | NM_030648 |
Protein Refseq : | NP_085151 |
MIM : | 606594 |
UniProt ID : | Q8WTS6 |
Products Types
◆ Recombinant Protein | ||
Setd7-5801M | Recombinant Mouse Setd7 Protein, Myc/DDK-tagged | +Inquiry |
SETD7-22H | Recombinant Human SETD7 Protein, His-tagged | +Inquiry |
SETD7-89H | Recombinant Human SET Domain-Containing Protein 7 | +Inquiry |
SETD7-3983R | Recombinant Rhesus Macaque SETD7 Protein, His (Fc)-Avi-tagged | +Inquiry |
SETD7-129H | Active Recombinant Human SETD7 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SETD7-1925HCL | Recombinant Human SETD7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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