Recombinant Human SETDB1 Protein (510-1290, end), N His-FLAG tagged
| Cat.No. : | SETDB1-12H |
| Product Overview : | Human SetDB1 (variant 2), also known as Histone-lysine Nmethyltransferase SETDB1, SET domain bifurcated 1, KMT1E, ERG-associated protein with SET domain (ESET), GenBank Accession No. NM_012432, a.a. 510-1290(end) expressed in a Baculovirus Sf9 cell expression system. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. |
| Source : | Sf9 insect cells |
| Species : | Human |
| Tag : | N His-GST |
| Form : | Aqueous buffer solution |
| Molecular Mass : | 114 kDa |
| Protein Length : | 510-1290, end |
| Purity : | ≥85% |
| Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Usage : | Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles. |
| Storage : | At least 6 months at -80 centigrade. |
| Storage Buffer : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% Glycerol and variable glutathione |
| Shipping : | At -80 centigrade |
| Warning : | Avoid freeze/thaw cycles |
| Gene Name : | SETDB1 SET domain, bifurcated 1 [ Homo sapiens (human) ] |
| Official Symbol : | SETDB1 |
| Synonyms : | SETDB1; SET domain, bifurcated 1; histone-lysine N-methyltransferase SETDB1; ESET; KG1T; KIAA0067; KMT1E; H3-K9-HMTase 4; lysine N-methyltransferase 1E; histone H3-K9 methyltransferase 4; ERG-associated protein with SET domain; ERG-associated protein with a SET domain, ESET; histone-lysine N-methyltransferase, H3lysine-9 specific 4; H3-K9-HMTase4 |
| Gene ID : | 9869 |
| mRNA Refseq : | NM_012432 |
| Protein Refseq : | NP_036564 |
| MIM : | 604396 |
| UniProt ID : | Q15047 |
Products Types
| ◆ Recombinant Protein | ||
| Setdb1-5802M | Recombinant Mouse Setdb1 Protein, Myc/DDK-tagged | +Inquiry |
| SETDB1-2120H | Recombinant Human SETDB1 Protein (1-397 aa), GST-tagged | +Inquiry |
| SETDB1-1986H | Recombinant Human SETDB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| SETDB1-6717H | Recombinant Human SETDB1 Protein (Met1-Ser350), N-His tagged | +Inquiry |
| SETDB1-70H | Active Recombinant Human SETDB1, FLAG-tagged | +Inquiry |
| ◆ Lysates | ||
| SETDB1-1923HCL | Recombinant Human SETDB1 293 Cell Lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-1865 | SetDB1 Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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