| Description : |
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
58.8 kDa |
| AA Sequence : |
METILEQQRRYHEEKERLMDVMAKE MLTKKSTLRDQINSDHRTRAMQDRY MEVSGNLRDLYDDKDGLRKEELNAI SGPNEFAEFYNRLKQIKEFHRKHPN EICVPMSVEFEELLKARENPSEEAQ NLVEFTDEEGYGRYLDLHDCYLKYI NLKASEKLDYITYLSIFDQLFDIPK ERKNAEYKRYLEMLLEYLQDYTDRV KPLQDQNELFGKIQAEFEKKWENGT FPGWPKETSSALTHAGAHLDLSAFS SWEELASLGLDRLKSALLALGLKCG GTLEERAQRLFSTKGKSLESLDTSL FAKNPKSKGTKRDTERNKDIAFLEA QIYEYVEILGEQRHLTHENVQRKQA RTGEEREEEEEEQISESESEDEENE IIYNPKNLPLGWDGKPIPYWLYKLH GLNINYNCEICGNYTYRGPKAFQRH FAEWRHAHGMRCLGIPNTAHFANVT QIEDAVSLWAKLKLQKASERWQPDT EEEYEDSSGNVVNKKTYEDLKRQGL LTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
