Recombinant Human SGMS2 Protein, GST-tagged

• Cat.No.: SGMS2-4336H
• Product Overview: Human MGC26963 full-length ORF ( NP_689834.1, 1 a.a. - 365 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 68.7 kDa
• AA Sequence: MDIIETAKLEEHLENQPSDPTNTYA RPAEPVEEENKNGNGKPKSLSSGLR KGTKKYPDYIQIAMPTESRNKFPLE WWKTGIAFIYAVFNLVLTTVMITVV HERVPPKELSPPLPDKFFDYIDRVK WAFSVSEINGIILVGLWITQWLFLR YKSIVGRRFCFIIGTLYLYRCITMY VTTLPVPGMHFQCAPKLNGDSQAKV QRILRLISGGGLSITGSHILCGDFL FSGHTVTLTLTYLFIKEYSPRHFWW YHLICWLLSAAGIICILVAHEHYTI DVIIAYYITTRLFWWYHSMANEKNL KVSSQTNFLSRAWWFPIFYFFEKNV QGSIPCCFSWPLSWPPGCFKSSCKK YSRVQKIGEDNEKST
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: SGMS2 sphingomyelin synthase 2 [ Homo sapiens ]
• Official Symbol: SGMS2
• Synonyms: SGMS2; sphingomyelin synthase 2; phosphatidylcholine:ceramide cholinephosphotransferase 2; MGC26963; SMS2; SM synthase
• Gene ID: 166929
• mRNA Refseq: NM_001136257
• Protein Refseq: NP_001129729
• MIM: 611574
• UniProt ID: Q8NHU3