Recombinant Human SGMS2 Protein, GST-tagged

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Recombinant Human SGMS2 Protein, GST-tagged

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Cat.No. : SGMS2-4336H
Product Overview : Human MGC26963 full-length ORF ( NP_689834.1, 1 a.a. - 365 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 68.7 kDa
AA Sequence : MDIIETAKLE EHLENQPSDP TNTYARPAEP VEEENKNGNG KPKSLSSGLR KGTKKYPDYI QIAMPTESRN KFPLEWWKTG IAFIYAVFNL VLTTVMITVV HERVPPKELS PPLPDKFFDY IDRVKWAFSV SEINGIILVG LWITQWLFLR YKSIVGRRFC FIIGTLYLYR CITMYVTTLP VPGMHFQCAP KLNGDSQAKV QRILRLISGG GLSITGSHIL CGDFLFSGHT VTLTLTYLFI KEYSPRHFWW YHLICWLLSA AGIICILVAH EHYTIDVIIA YYITTRLFWW YHSMANEKNL KVSSQTNFLS RAWWFPIFYF FEKNVQGSIP CCFSWPLSWP PGCFKSSCKK YSRVQKIGED NEKST
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : SGMS2 sphingomyelin synthase 2 [ Homo sapiens ]
Official Symbol : SGMS2
Synonyms : SGMS2; sphingomyelin synthase 2; phosphatidylcholine:ceramide cholinephosphotransferase 2; MGC26963; SMS2; SM synthase;
Gene ID : 166929
mRNA Refseq : NM_001136257
Protein Refseq : NP_001129729
MIM : 611574
UniProt ID : Q8NHU3

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