Recombinant Human SH2B3 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | SH2B3-3773H |
| Product Overview : | SH2B3 MS Standard C13 and N15-labeled recombinant protein (NP_005466) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 63 kDa |
| AA Sequence : | MNGPALQPSS PSSAPSASPA AAPRGWSEFC ELHAVAAARE LARQYWLFAR EHPQHAPLRA ELVSLQFTDL FQRYFCREVR DGRAPGRDYR DTGRGPPAKA EASPEPGPGP AAPGLPKARS SEELAPPRPP GPCSFQHFRR SLRHIFRRRS AGELPAAHTA AAPGTPGEAA ETPARPGLAK KFLPWSLARE PPPEALKEAV LRYSLADEAS MDSGARWQRG RLALRRAPGP DGPDRVLELF DPPKSSRPKL QAACSSIQEV RRCTRLEMPD NLYTFVLKVK DRTDIIFEVG DEQQLNSWMA ELSECTGRGL ESTEAEMHIP SALEPSTSSS PRGSTDSLNQ GASPGGLLDP ACQKTDHFLS CYPWFHGPIS RVKAAQLVQL QGPDAHGVFL VRQSETRRGE YVLTFNFQGI AKHLRLSLTE RGQCRVQHLH FPSVVDMLHH FQRSPIPLEC GAACDVRLSS YVVVVSQPPG SCNTVLFPFS LPHWDSESLP HWGSELGLPH LSSSGCPRGL SPEGLPGRSS PPEQIFHLVP SPEELANSLQ HLEHEPVNRA RDSDYEMDSS SRSHLRAIDN QYTPLTRTRP LEQKLISEED LAANDILDYK DDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | SH2B3 SH2B adaptor protein 3 [ Homo sapiens (human) ] |
| Official Symbol : | SH2B3 |
| Synonyms : | SH2B3; SH2B adaptor protein 3; SH2B adapter protein 3; IDDM20; LNK; lymphocyte adaptor protein; signal transduction protein Lnk; lymphocyte-specific adapter protein Lnk; |
| Gene ID : | 10019 |
| mRNA Refseq : | NM_005475 |
| Protein Refseq : | NP_005466 |
| MIM : | 605093 |
| UniProt ID : | Q9UQQ2 |
◆ Recombinant Protein
| Sh2b3-1332M | Recombinant Mouse Sh2b3 Protein, MYC/DDK-tagged | +Inquiry |
| Sh2b3-1557M | Recombinant Mouse Sh2b3 protein, His & T7-tagged | +Inquiry |
| SH2B3-5373R | Recombinant Rat SH2B3 Protein | +Inquiry |
| SH2B3-15053M | Recombinant Mouse SH2B3 Protein | +Inquiry |
| SH2B3-2638H | Recombinant Human SH2B3, His-tagged | +Inquiry |
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◆ Lysates
| SH2B3-1880HCL | Recombinant Human SH2B3 293 Cell Lysate | +Inquiry |
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SH2D1ASH3BGRSH2B1SH2D3CSH2D4ASH3BGRLSH3BP2SH3BP4SH3BP5SH3D19SH3GL2SH3GLB1SH3RF1SH3RF2SH3GL1SH2B3SH2D1BSH2D3ASH2B2SH3D21SH3PXD2ASH2D4BSH2D5SH3TC2SH3GL3SH3GLB2SH3KBP1SH3TC1SH2D2ASH3BP1SH3BGRL2SH3BGRL3SH3BP5LSH3YL1Sh2d1b1SH2D6Sh2d1b2SH3PXD2BSH3RF3Sh2d7
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