Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: SHC4-355H
• Product Overview: SHC4 MS Standard C13 and N15-labeled recombinant protein (NP_976224) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 68.7 kDa
• AA Sequence: MRERGQDSLAGLVLYVGLFGHPGML HRAKYSRFRNESITSLDEGSSGGSV GDKGSPQPPHPALAPHLPTEDATLP SQESPTPLCTLIPRMASMKLANPAT LLSLKNFCLGTKEVPRLKLQESRDP GSSGPSSPETSLSRSGTAPPPQQDL VGHRATALTPDSCPLPGPGEPTLRS RQDRHFLQHLLGMGMNYCVRYMGCV EVLQSMRSLDFGMRTQVTREAISRL CEAVPGANGAIKKRKPPVEFLSTVL GKSNLQFSGMNIKLTISTCSLTLMN LDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECHNG MAQDVISTIGQAFELRFKQYLKNPS LNTSCESEEVHIDSHAEEREDHEYY NEIPGKQPPVGGVSDMRIKVQATEQ MAYCPIQCEKLCYLPGNSKCSSVYE NCLEQSRAIGNVHPRGVQSQRGTSL LKHTCRVDLFDDPCYINTQALQSTP GSAGNQRSAQPLGSPWHCGKAPETV QPGATAQPASSHSLPHIKQQLWSEE CYHGKLSRKAAESLLVKDGDFLVRE SATSPGQYVLSGLQGGQAKHLLLVD PEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPAL LHSNKTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SHC4 SHC (Src homology 2 domain containing) family, member 4 [ Homo sapiens (human) ]
• Official Symbol: SHC4
• Synonyms: SHC4; SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4; rai like protein; RaLP; hShcD; rai-like protein; SH2 domain protein C4; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4; SHCD; MGC34023
• Gene ID: 399694
• mRNA Refseq: NM_203349
• Protein Refseq: NP_976224
• MIM: 600781
• UniProt ID: Q6S5L8