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Recombinant Human SIGLEC8 protein, His-Avi-tagged, Biotinylated

Cat.No. : SIGLEC8-197HB
Product Overview : Biotinylated Recombinant human siglec 8 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Met17-Ala363.
  • Specification
  • Gene Information
  • Related Products
Description : Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in 20mM PBS,pH7.4.
Molecular Mass : The protein has a predicted MW of 40.7 kDa.Due to glycosylation, the protein migrates to 50-60KDa based on Bis-Tris PAGE result.
Protein length : It contains Met17-Ala363.
Endotoxin : Less than 0.05 EU per ug by the LAL method.
Purity : > 95% as determined by Tris-Bis -PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : SIGLEC8 sialic acid binding Ig-like lectin 8 [ Homo sapiens ]
Official Symbol : SIGLEC8
Synonyms : SAF2; SIGLEC-8; SIGLEC8L
Gene ID : 27181
mRNA Refseq : NM_014442
Protein Refseq : NP_055257
MIM : 605639
UniProt ID : Q9NYZ4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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