"SIGMAR1" Related Products


Recombinant Human SIGMAR1 protein, MYC/DDK-tagged

Cat.No.: SIGMAR1-12H
Product Overview: Recombinant Human SIGMAR1, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 24.9 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: SIGMAR1 sigma non-opioid intracellular receptor 1 [ Homo sapiens ]
Official Symbol: SIGMAR1
Synonyms: SIGMAR1; sigma non-opioid intracellular receptor 1; opioid receptor, sigma 1 , OPRS1; SR BP1; SR-BP; SIG-1R; sigma1R; hSigmaR1; SR31747 binding protein 1; sigma 1-type opioid receptor; aging-associated gene 8 protein; SRBP; ALS16; OPRS1; SR-BP1; MGC3851; FLJ25585;
Gene ID: 10280
mRNA Refseq: NM_005866
Protein Refseq: NP_005857
MIM: 601978
UniProt ID: Q99720
Chromosome Location: 9p13.3
Function: C-8 sterol isomerase activity; drug binding; opioid receptor activity; receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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