Recombinant Human SIRPB1 protein, Fc-tagged
Cat.No. : | SIRPB1-345H |
Product Overview : | Recombinant Human SIRPB1 protein (Glu30-Leu371), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRPβ1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. SIRPβ1 is a transmembrane protein that has three Ig-like domains in its extracellular region and a short cytoplasmic tail. Human SIRPβ1 is expressed on monocytes and granulocytes but not on lymphocytes. SIRP beta 1 contains short cytoplasmic domains that lack cytoplasmic sequence motifs capable of recruiting SHP-2 and SHP-1. In addition, they contain a single basic lysine residue within the hydrophobic transmembrane domain. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 63.7 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 342 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | SIRPB1 |
Official Symbol : | SIRPB1 |
Synonyms : | SIRPB1; signal-regulatory protein beta 1; signal-regulatory protein beta-1; CD172b; SIRP BETA 1; CD172 antigen-like family member B; SIRP-BETA-1; FLJ26614; DKFZp686A05192 |
Gene ID : | 10326 |
mRNA Refseq : | NM_001083910 |
Protein Refseq : | NP_001077379 |
MIM : | 603889 |
UniProt ID : | O00241 |
Products Types
◆ Recombinant Protein | ||
SIRPB1-2089H | Recombinant Human SIRPB1 Protein (30-371 aa), His-tagged | +Inquiry |
SIRPB1-006H | Recombinant Human SIRPB1 Protein, C-His-tagged | +Inquiry |
SIRPB1-001H | Recombinant Human SIRPB1 Protein, His-tagged | +Inquiry |
SIRPB1-2013H | Recombinant Human SIRPB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIRPB1-3890H | Recombinant Human SIRPB1 Protein (Met1-Leu371), C-His tagged | +Inquiry |
◆ Lysates | ||
SIRPB1-1608HCL | Recombinant Human SIRPB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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