Recombinant Human SIRPB1 protein, His-Avi-tagged

• Cat.No.: SIRPB1-241H
• Product Overview: Human SIRP beta Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Glu30-Ala369.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Glu30-Ala369
• Description: SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a Vset Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 40 KDa. Due to glycosylation, the protein migrates to 52- 60KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.001EU per ug by the LAL method.
• Purity: > 95% as determined by SDS-PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: SIRPB1 signal regulatory protein beta 1[ Homo sapiens (human) ]
• Official Symbol: SIRPB1
• Synonyms: CD172 antigen-like family member B; CD172b antigen; CD172b; DKFZp686A05192; FLJ26614; signal-regulatory protein beta 1; signal-regulatory protein beta-1; SIRP beta 1; SIRPB1; SIRP-beta-1 isoform 3; SIRP-BETA-1
• Gene ID: 10326
• mRNA Refseq: NM_001083910.4
• Protein Refseq: NP_001077379.1
• MIM: 603889
• UniProt ID: O00241