Recombinant Human SIRPB1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SIRPB1-6667H
• Product Overview: SIRPB1 MS Standard C13 and N15-labeled recombinant protein (NP_001129316) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 43.2 kDa
• AA Sequence: MPVPASWPHLPSPFLLMTLLLGRLTGVAGEDELQVIQPEKSVSVAAGESATLCCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEMAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEPALAPTAPLLVALLLGPKLLLVVGVSAIYICWKQKATRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SIRPB1 signal-regulatory protein beta 1 [ Homo sapiens (human) ]
• Official Symbol: SIRPB1
• Synonyms: SIRPB1; signal-regulatory protein beta 1; signal-regulatory protein beta-1; CD172b; SIRP BETA 1; CD172 antigen-like family member B; SIRP-BETA-1; FLJ26614; DKFZp686A05192
• Gene ID: 10326
• mRNA Refseq: NM_001135844
• Protein Refseq: NP_001129316
• MIM: 603889
• UniProt ID: O00241