Recombinant Human SIRT6 Protein, His-tagged

• Cat.No.: SIRT6-24H
• Product Overview: Recombinant human SIRT6(1-355) protein with a N-terminal His-tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-355
• Description: This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Molecular Mass: 43.7 kDa
• Purity: ≥80% estimated by SDS-PAGE
• Stability: ≥ 6 months
• Storage: Store it at -80 centigrade
• Storage Buffer: 25 mM Tris-HCl, pH 8.0, with 100mM NaCl, 20% glycerol

Gene Information

• Gene Name: SIRT6 sirtuin 6 [ Homo sapiens (human) ]
• Official Symbol: SIRT6
• Synonyms: SIRT6; sirtuin 6; SIR2L6; NAD-dependent protein deacetylase sirtuin-6; SIR2-like protein 6; regulatory protein SIR2 homolog 6; sir2-related protein type 6; sirtuin type 6
• Gene ID: 51548
• mRNA Refseq: NM_001193285
• Protein Refseq: NP_001180214
• MIM: 606211
• UniProt ID: Q8N6T7