Recombinant Human SKIL
Cat.No. : | SKIL-27723TH |
Product Overview : | Recombinant full length Human SnoN with a N terminal proprietary tag: predicted molecular weight 101.31 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
Protein length : | 684 amino acids |
Molecular Weight : | 101.310kDa |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHVNG KTINKVPTVKKEHLDDYGEAPVETDGEHVKRTCTSVPETL HLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVG GEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSD QLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQF YVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGF ESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSY YLYMCDKVVAPNVSLTSAVSQSKELTKTEASKSISRQSEK AHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKD VICEDDKGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVK MLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRL DHAEADRQELQDELRQEREARQKLEMMIKELKLQILKSSK TAKE |
Gene Name : | SKIL SKI-like oncogene [ Homo sapiens ] |
Official Symbol : | SKIL |
Synonyms : | SKIL; SKI-like oncogene; ski-like protein; SNO; SnoA; SnoN; |
Gene ID : | 6498 |
mRNA Refseq : | NM_001145098 |
Protein Refseq : | NP_001138570 |
MIM : | 165340 |
Uniprot ID : | P12757 |
Chromosome Location : | 3q26 |
Pathway : | Regulation of nuclear SMAD2/3 signaling, organism-specific biosystem; TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; TGF-beta receptor signaling, organism-specific biosystem; |
Function : | NOT DNA binding; SMAD binding; chromatin binding; chromatin binding; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
SKIL-6729C | Recombinant Chicken SKIL | +Inquiry |
SKIL-27724TH | Recombinant Human SKIL | +Inquiry |
SKIL-2688H | Recombinant Human SKIL, His-tagged | +Inquiry |
◆ Lysates | ||
SKIL-1814HCL | Recombinant Human SKIL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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