Recombinant Human SLAMF7 protein, His-Avi-tagged
Cat.No. : | SLAMF7-107H |
Product Overview : | Recombinant Human SLAMF7 protein(Q9NQ25-1)(Ser23-Met226), fused with C-terminal His and Avi tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-His-Avi |
Protein length : | Ser23-Met226 |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human SLAMF7, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-SLAMF7 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Storage : | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Gene Name : | SLAMF7 SLAM family member 7 [ Homo sapiens ] |
Official Symbol : | SLAMF7 |
Synonyms : | SLAMF7; SLAM family member 7; 19A; CD319; CRACC; CS1; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein; |
Gene ID : | 57823 |
mRNA Refseq : | NM_021181 |
Protein Refseq : | NP_067004 |
MIM : | 606625 |
UniProt ID : | Q9NQ25 |
Products Types
◆ Recombinant Protein | ||
SLAMF7-294H | Recombinant Human SLAMF7 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
SLAMF7-121H | Recombinant Human SLAMF7 Protein, His-tagged | +Inquiry |
SLAMF7-2328H | Recombinant Human SLAMF7 protein(Met1-Met226), hFc-tagged, Biotinylated | +Inquiry |
SLAMF7-449H | Recombinant Full Length Human SLAMF7 Protein, Fc-tagged | +Inquiry |
SLAMF7-0692H | Recombinant Human SLAMF7 protein, hFc-tagged | +Inquiry |
◆ Lysates | ||
SLAMF7-2591MCL | Recombinant Mouse SLAMF7 cell lysate | +Inquiry |
SLAMF7-2378HCL | Recombinant Human SLAMF7 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewIt has a high solubility and can be easily prepared at the desired concentration.
It was found to be well active and could effectively perform the required biological activity experiments.
It was observed that SLAMF7 had good crystallinity, which was conducive to crystallography research.
Q&As (6)
Ask a questionSLAMF7 protein is involved in regulating immune cell activation, proliferation, and transmission of background signals by binding to activating ligands, such as CD319, thereby influencing the immune response.
By combining with immunotherapy, such as anti-PD-1 antibodies, the immune response can be further enhanced and the anti-tumor effect can be improved. The study of SLAMF7 protein provides a new direction for the development of combinatorial therapeutic strategies.
This protein is mainly expressed in the immune system, including immune cells such as plasma cells, NK cells, and activated T cells.
The role of SLAMF7 protein in other types of cancer is unclear, and further research is needed to determine its potential role in other cancers.
Yes, the SLAMF7 protein has been shown to be a potential therapeutic target. A monoclonal antibody drug targeting SLAMF7 protein (Elotuzumab) has been developed for the treatment of multiple myeloma.
SLAMF7 protein interacts with NK cells in multiple myeloma and plays a role in inhibiting and controlling tumor growth by activating the anti-tumor activity of NK cells.
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