Recombinant Human SLC26A4 protein, MYC/DDK-tagged
Cat.No. : | SLC26A4-318H |
Product Overview : | Recombinant Human SLC26A4 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
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Description : | Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 85.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | SLC26A4 solute carrier family 26, member 4 [ Homo sapiens ] |
Official Symbol : | SLC26A4 |
Synonyms : | SLC26A4; solute carrier family 26, member 4; DFNB4; pendrin; PDS; sodium-independent chloride/iodide transporter; EVA; TDH2B; |
Gene ID : | 5172 |
mRNA Refseq : | NM_000441 |
Protein Refseq : | NP_000432 |
MIM : | 605646 |
UniProt ID : | O43511 |
Chromosome Location : | 7q31 |
Pathway : | Multifunctional anion exchangers, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem; |
Function : | chloride transmembrane transporter activity; iodide transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; transporter activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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