"SLC5A5" Related Products

Recombinant Human SLC5A5 HEK293T cell lysate

Cat.No.: SLC5A5-82HCL
Product Overview: Human SLC5A5 was derived from Human HEK293T cell line.
Description: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.
Source: HEK293T
Species: Human
Tag: C-terminal Myc/DDK
Form: The cell lysate is provided in RIPA buffer.
Molecular Mass: 68.5 kDa
Usage: 1 vial of 100 µg gene specific transient over-expression cell lysate in RIPA buffer1 vial of 100 µg empty vector transfected control cell lysate in RIPA buffer1 vial of 250ul 2xSDS Sample Buffer (4% SDS, 125mM Tris-HCl pH6.8, 10% Glycerol, 0.002% Bromphenol blue, 100mM DTT)
Storage: The lysate is shipped with dry ice. Upon receiving, store the sample at -20 centigrade. Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade. Avoid repeated freeze-thaw cycles.Lysate samples can be diluted with 2xSDS Sample Buffer provided. After dilution, the protein sample should be aliquoted and stored at -20 centigrade for long term storage. Prior to SDS-PAGE fractionation, boil the lysate for 5 minutes.
Gene Name: SLC5A5 solute carrier family 5 (sodium iodide symporter), member 5 [ Homo sapiens ]
Official Symbol: SLC5A5
Synonyms: SLC5A5; solute carrier family 5 (sodium iodide symporter), member 5; sodium/iodide cotransporter; NIS; Na(+)/I(-) symporter; Na(+)/I(-) cotransporter; TDH1;
Gene ID: 6528
mRNA Refseq: NM_000453
Protein Refseq: NP_000444
MIM: 601843
UniProt ID: Q92911
Chromosome Location: 19p13.2-p12
Pathway: Amine-derived hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Organic anion transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Thyroxine biosynthesis, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
Function: iodide transmembrane transporter activity; sodium:iodide symporter activity; symporter activity; transporter activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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