Recombinant Human SMAD6 Protein, His-tagged

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Recombinant Human SMAD6 Protein, His-tagged

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Cat.No. : PGC-299H
Product Overview : Recombinant Human SMAD6(Cys261~Pro495) fused with His tag at N-terminal was expressed in E. coli.
Description : The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 29.7kDa
Protein length : Cys261~Pro495
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Figure :

Gene Name : SMAD6 SMAD family member 6 [ Homo sapiens ]
Official Symbol : SMAD6
Synonyms : SMAD6; SMAD family member 6; MAD, mothers against decapentaplegic homolog 6 (Drosophila) , MADH6, MADH7, SMAD, mothers against DPP homolog 6 (Drosophila); mothers against decapentaplegic homolog 6; HsT17432; SMAD 6; hSMAD6; MAD homolog 6; mothers against DPP homolog 6; SMAD, mothers against DPP homolog 6; Mothers against decapentaplegic, drosophila, homolog of, 6; MADH6; MADH7;
Gene ID : 4091
mRNA Refseq : NM_001142861
Protein Refseq : NP_001136333
MIM : 602931
UniProt ID : O43541
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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