Recombinant Mouse Smad6 Protein, Myc/DDK-tagged
Cat.No. : | Smad6-5953M |
Product Overview : | Purified recombinant protein of mouse full-length SMAD family member 6 (Smad6), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Binds to regulatory elements in target promoter regions. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 54.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Smad6 SMAD family member 6 [ Mus musculus (house mouse) ] |
Official Symbol : | Smad6 |
Synonyms : | SMAD6; MAD homolog 6 (Drosophila); mothers against decapentaplegic homolog 6; Smad 6; mad homolog 7; SMAD family member 6; mothers against DPP homolog 6; Madh6 |
Gene ID : | 17130 |
mRNA Refseq : | NM_008542 |
Protein Refseq : | NP_032568 |
UniProt ID : | O35182 |
Products Types
◆ Recombinant Protein | ||
Smad6-300M | Recombinant Mouse Smad6 Protein, His-tagged | +Inquiry |
SMAD6-8458M | Recombinant Mouse SMAD6 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMAD6-22H | Recombinant Human SMAD6 Protein, GST-tagged | +Inquiry |
Smad6-301R | Recombinant Rat Smad6 Protein, His-tagged | +Inquiry |
PGC-299H | Recombinant Human SMAD6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SMAD6-1644HCL | Recombinant Human SMAD6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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