Recombinant Human SNCA Protein, Myc/DDK-tagged, C13 and N15-labeled SNCA-6456H

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Recombinant Human SNCA Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	SNCA-6456H
Product Overview :	SNCA MS Standard C13 and N15-labeled recombinant protein (NP_000336) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	14.3 kDa
AA Sequence :	MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	SNCA synuclein alpha [ Homo sapiens (human) ]
Official Symbol :	SNCA
Synonyms :	SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC110988;
Gene ID :	6622
mRNA Refseq :	NM_000345
Protein Refseq :	NP_000336
MIM :	163890
UniProt ID :	P37840