Recombinant Human SNCB Protein, MYC/DDK-tagged
Cat.No. : | SNCB-245H |
Product Overview : | Recombinant protein of human synuclein, beta (SNCB), transcript variant 1 with MYC/DDK at C-terminal was expressed in HEK293T. |
- Specification
- Gene Information
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Description : | Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 14.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at –80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | SNCB |
Official Symbol : | SNCB synuclein beta [ Homo sapiens (human) ] |
Synonyms : | SNCB; synuclein beta; beta-synuclein; I(2)-synuclein |
Gene ID : | 6620 |
mRNA Refseq : | NM_003085 |
Protein Refseq : | NP_003076 |
MIM : | 602569 |
UniProt ID : | Q16143 |
Products Types
◆ Recombinant Protein | ||
Sncb-249M | Recombinant Mouse Sncb Protein, MYC/DDK-tagged | +Inquiry |
SNCB-2056H | Recombinant Human SNCB Protein, His (Fc)-Avi-tagged | +Inquiry |
SNCB-5298R | Recombinant Rat SNCB Protein, His (Fc)-Avi-tagged | +Inquiry |
SNCB-2457M | Recombinant Mouse SNCB Protein (1-133 aa) | +Inquiry |
SNCB-4182R | Recombinant Rhesus Macaque SNCB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
SNCB-27206TH | Native Human SNCB | +Inquiry |
◆ Lysates | ||
SNCB-1632HCL | Recombinant Human SNCB 293 Cell Lysate | +Inquiry |
SNCB-1631HCL | Recombinant Human SNCB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMutations in the SNCB gene have been identified in certain cases of familial Parkinson's disease, suggesting a genetic link to the disease.
Positron emission tomography (PET) imaging using specific radiotracers has shown promise in visualizing SNCB protein aggregates in the brain.
SNCB protein has been found to interact with alpha-synuclein and other proteins in the brain, potentially influencing disease pathogenesis.
Future research directions include further validation of SNCB protein as a biomarker, development of targeted therapeutic interventions, and understanding the molecular mechanisms underlying its role in neurodegenerative diseases.
Studies have suggested that alterations in SNCB protein levels may correlate with disease severity and progression in neurodegenerative diseases.
Customer Reviews (3)
Write a reviewHighly recommended!
The SNCB protein is undoubtedly a superior choice, boasting extraordinary quality that guarantees it will fulfill all my experimental requirements.
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