Recombinant Human SNUPN Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SNUPN Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : SNUPN-5084H
Product Overview : SNUPN MS Standard C13 and N15-labeled recombinant protein (NP_001036053) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 41.1 kDa
AA Sequence : MEELSQALAS SFSVSQDLNS TAAPHPRLSQ YKSKYSSLEQ SERRRRLLEL QKSKRLDYVN HARRLAEDDW TGMESEEENK KDDEEMDIDT VKKLPKHYAN QLMLSEWLID VPSDLGQEWI VVVCPVGKRA LIVASRGSTS AYTKSGYCVN RFSSLLPGGN RRNSTAKDYT ILDCIYNEVN QTYYVLDVMC WRGHPFYDCQ TDFRFYWMHS KLPEEEGLGE KTKLNPFKFV GLKNFPCTPE SLCDVLSMDF PFEVDGLLFY HKQTHYSPGS TPLVGWLRPY MVSDVLGVAV PAGPLTTKPD YAGHQLQQIM EHKKSQKEGM KEKLTHKASE NGHYELEHLS TPKLKGSSHS PDHPGCLMEN TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SNUPN snurportin 1 [ Homo sapiens (human) ]
Official Symbol : SNUPN
Synonyms : SNUPN; snurportin 1; RNA, U transporter 1, RNUT1; snurportin-1; SNURPORTIN 1; Snurportin1; RNA U transporter 1; RNA, U transporter 1; KPNBL; RNUT1;
Gene ID : 10073
mRNA Refseq : NM_001042588
Protein Refseq : NP_001036053
MIM : 607902
UniProt ID : O95149

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