Recombinant Human SOX2

• Cat.No.: SOX2-966H
• Product Overview: Recombinant Human SOX2 fussed with poly-arginine tag at C-terminal was expressed in E. coli, which was a single, non-glycosylated, Polypeptide chain protein.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 317 amino acid
• Description: SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency.
• Form: The SOX2 solution (0.15mg/ml) contains 20mM PBS.
• Molecular Mass: 34.3kDa
• Purity: Greater than 95.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE.
• Usage: LABORATORY RESEARCH USE ONLY
• Stability: SOX2 Human Recombinant although stable at 4 centigrade for 1 week, should be stored below -18 centigrade.Please prevent freeze thaw cycles.

Gene Information

• Gene Name: SOX2 SRY (sex determining region Y)-box 2 [ Homo sapiens ]
• Official Symbol: SOX2
• Synonyms: ANOP3; MCOPS3; transcription factor SOX-2; SRY-related HMG-box gene 2; transcription factor SOX2
• Gene ID: 6657
• mRNA Refseq: NM_003106
• Protein Refseq: NP_003097
• MIM: 184429
• UniProt ID: P48431
• Chromosome Location: 3q26.3-q27
• Pathway: Cardiac Progenitor Differentiation, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Hippo signaling pathway, organism-specific biosystem
• Function: DNA binding; chromatin binding; miRNA binding