Description : |
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
89.7 kDa |
AA Sequence : |
MSSKQATSPFACAADGEDAMTQDLT SREKEEGSDQHVASHLPLHPIMHNK PHSEELPTLVSTIQQDADWDSVLSS QQRMESENNKLCSLYSFRNTSTSPH KPDEGSRDREIMTSVTFGTPERRKG SLADVVDTLKQKKLEEMTRTEQEDS SCMEKLLSKDWKEKMERLNTSELLG EIKGTPESLAEKERQLSTMITQLIS LREQLLAAHDEQKKLAASQIEKQRQ QMDLARQQQEQIARQQQQLLQQQHK INLLQQQIQVQGHMPPLMIPIFPHD QRTLAAAAAAQQGFLFPPGITYKPG DNYPVQFIPSTMAAAAASGLSPLQL QKGHVSHPQINQRLKGLSDRFGRNL DTFEHGGGHSYNHKQIEQLYAAQLA SMQVSPGAKMPSTPQPPNTAGTVSP TGIKNEKRGTSPVTQVKDEAAAQPL NLSSRPKTAEPVKSPTSPTQNLFPA SKTSPVNLPNKSSIPSPIGGSLGRG SSLDILSSLNSPALFGDQDTVMKAI QEARKMREQIQREQQQQQPHGVDGK LSSINNMGLNSCRNEKERTRFENLG PQLTGKSNEDGKLGPGVIDLTRPED AEGGATVAEARVYRDARGRASSEPH IKRPMNAFMVWAKDERRKILQAFPD MHNSNISKILGSRWKSMSNQEKQPY YEEQARLSKIHLEKYPNYKYKPRPK RTCIVDGKKLRIGEYKQLMRSRRQE MRQFFTVGQQPQIPITTGTGVVYPG AITMATTTPSPQMTSDCSSTSASPE PSLPVIQSTYGMKTDGGSLAGNEMI NGEDEMEMYDDYEDDPKSDYSSENE APEAVSANTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |