Recombinant Human SP1 protein, His-tagged
Cat.No. : | SP1-16H |
Product Overview : | Recombinant Human SP1 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 50mM Tris, 8M Urea, pH8.0. |
Molecular Mass : | 80.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | SP1 Sp1 transcription factor [ Homo sapiens ] |
Official Symbol : | SP1 |
Synonyms : | SP1; Sp1 transcription factor; transcription factor Sp1; specificity protein 1; |
Gene ID : | 6667 |
mRNA Refseq : | NM_001251825 |
Protein Refseq : | NP_001238754 |
MIM : | 189906 |
UniProt ID : | P08047 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSP1 plays a role in immune response by regulating the expression of genes involved in inflammation and immune cell function. Its modulation can influence the immune system's response to various stimuli.
Yes, SP1 is implicated in cardiovascular diseases by regulating genes involved in vascular smooth muscle cell proliferation and migration. Targeting SP1 may offer therapeutic avenues for cardiovascular conditions.
Yes, SP1 has been implicated in neurodegenerative diseases. Its role in regulating genes related to neuronal survival and death makes it a target for exploring therapeutic interventions in conditions like Alzheimer's disease.
Yes, elevated levels of SP1 have been observed in certain cancers. Detection of SP1 expression can potentially serve as a diagnostic marker, aiding in the early identification of cancer.
SP1 regulates the expression of genes involved in angiogenesis, the formation of new blood vessels. Increased SP1 activity is associated with enhanced angiogenesis, which can be critical in wound healing and tumor growth.
Customer Reviews (3)
Write a reviewIn addition to their expertise, the manufacturer's technical support team can assist in troubleshooting and optimizing the handling and application of the SP1 protein.
Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various disciplines.
By relying on the SP1 protein and the manufacturer's exceptional technical support, researchers can confidently pursue their experimental goals while knowing they have access to reliable resources and expert guidance.
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