Recombinant Human SPINT2 Protein, MYC/DDK-tagged

• Cat.No.: SPINT2-2686H
• Product Overview: Recombinant Human SPINT2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 25.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SPINT2 serine peptidase inhibitor, Kunitz type, 2 [ Homo sapiens ]
• Official Symbol: SPINT2
• Synonyms: DIAR3; HAI-2; HAI2; Kop; PB
• Gene ID: 10653
• mRNA Refseq: NM_001166103
• Protein Refseq: NP_001159575
• MIM: 605124
• UniProt ID: O43291