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Recombinant Human SPR Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | SPR-5524H |
Product Overview : | SPR MS Standard C13 and N15-labeled recombinant protein (NP_003115) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 28 kDa |
AA Sequence : | MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS MLCLTSSVLK AFPDSPGLNR TVVNISSLCA LQPFKGWALY CAGKAARDML FQVLALEEPN VRVLNYAPGP LDTDMQQLAR ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD KTRTRPLEQK LISEEDLAAN DILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | SPR sepiapterin reductase [ Homo sapiens (human) ] |
Official Symbol : | SPR |
Synonyms : | SPR; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; SDR38C1; short chain dehydrogenase/reductase family 38C; member 1; short chain dehydrogenase/reductase family 38C, member 1; |
Gene ID : | 6697 |
mRNA Refseq : | NM_003124 |
Protein Refseq : | NP_003115 |
MIM : | 182125 |
UniProt ID : | P35270 |
◆ Recombinant Protein
Spr-6107M | Recombinant Mouse Spr Protein, Myc/DDK-tagged | +Inquiry |
Spr-682M | Recombinant Mouse Spr Protein, His-tagged | +Inquiry |
SPR-681H | Recombinant Human SPR Protein, His/GST-tagged | +Inquiry |
Spr-205M | Recombinant Mouse Spr Protein, His-tagged | +Inquiry |
SPR-2931H | Recombinant Human SPR, GST-tagged | +Inquiry |
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◆ Lysates
SPR-1499HCL | Recombinant Human SPR 293 Cell Lysate | +Inquiry |
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