Recombinant Human SPR Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SPR Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : SPR-5524H
Product Overview : SPR MS Standard C13 and N15-labeled recombinant protein (NP_003115) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 28 kDa
AA Sequence : MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS MLCLTSSVLK AFPDSPGLNR TVVNISSLCA LQPFKGWALY CAGKAARDML FQVLALEEPN VRVLNYAPGP LDTDMQQLAR ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD KTRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SPR sepiapterin reductase [ Homo sapiens (human) ]
Official Symbol : SPR
Synonyms : SPR; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; SDR38C1; short chain dehydrogenase/reductase family 38C; member 1; short chain dehydrogenase/reductase family 38C, member 1;
Gene ID : 6697
mRNA Refseq : NM_003124
Protein Refseq : NP_003115
MIM : 182125
UniProt ID : P35270

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