Recombinant Human SRC protein, Flag-tagged, Biotinylated
Cat.No. : | SRC-79H |
Product Overview : | Recombinant Human SRC [1-536(end) amino acids of accession number NP_005408.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated. |
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Source : | Insect cell |
Species : | Human |
Tag : | Flag |
Form : | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5 |
Molecular Mass : | 64 kDa |
Purity : | >90% as determined by SDS-PAGE and CBB staining |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Protein length : | 1-536 |
Gene Name : | SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | SRC |
Synonyms : | SRC; ASV; c src; SRC1; c-SRC; p60-Src; |
Gene ID : | 6714 |
mRNA Refseq : | NM_005417 |
Protein Refseq : | NP_005408 |
MIM : | 190090 |
UniProt ID : | P12931 |
Chromosome Location : | 20q12-q13 |
Pathway : | ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; |
Function : | ATP binding; SH2 domain binding; SH3/SH2 adaptor activity; ephrin receptor binding; heme binding; integrin binding; ion channel binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein kinase activity; protein tyrosine kinase activity; receptor binding; |
Products Types
◆ Recombinant Protein | ||
SRC-0403H | Recombinant Human SRC Protein (G2-L536), His/Flag tagged | +Inquiry |
SRC-0402H | Recombinant Human SRC Protein (G2-L536), Tag Free | +Inquiry |
SRC-004H | Active Recombinant Human SRC Protein, GST-tagged | +Inquiry |
SRC-4276R | Recombinant Rhesus Macaque SRC Protein, His (Fc)-Avi-tagged | +Inquiry |
SRC-2747H | Recombinant Human SRC Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
SRC-29697TH | Native Human SRC | +Inquiry |
◆ Lysates | ||
SRC-585MCL | Recombinant Mouse SRC cell lysate | +Inquiry |
SRC-487HCL | Recombinant Human SRC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionChanges in SRC expression or kinase activity can lead to drug resistance in cancer treatment.
SRC regulates cell proliferation and survival through its kinase activity, influencing various signaling pathways.
SRC is involved in bone remodeling, regulating osteoclast activity and bone resorption.
SRC plays a crucial role in cancer progression, particularly in enhancing metastatic potential of tumor cells.
SRC influences key cellular signaling pathways like Ras/MAPK and PI3K/Akt, affecting cell growth and survival.
SRC modulates cellular adhesion and migration, playing a role in tissue repair and cancer metastasis.
SRC inhibition is a target in cancer therapy, potentially reducing tumor growth and metastasis.
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