| Description : |
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
51.4 kDa |
| AA Sequence : |
MLPTQAGAAAALGRGSALGGSLNRT PTGRPGGGGGTRGANGGRVPGNGAG LGPGRLEREAAAAAATTPAPTAGAL YSGSEGDSESGEEEELGAERRGLKR SLSEMEIGMVVGGPEASAAATGGYG PVSGAVSGAKPGKKTRGRVKIKMEF IDNKLRRYTTFSKRKTGIMKKAYEL STLTGTQVLLLVASETGHVYTFATR KLQPMITSETGKALIQTCLNSPDSP PRSDPTTDQRMSATGFEETDLTYQV SESDSSGETKDTLKPAFTVTNLPGT TSTIQTAPSTSTTMQVSSGPSFPIT NYLAPVSASVSPSAVSSANGTVLKS TGSGPVSSGGLMQLPTSFTLMPGGA VAQQVPVQAIQVHQAPQQASPSRDS STDLTQTSSSGTVTLPATIMTSSVP TTVGGHMMYPSPHAVMYAPTSGLGD GSLTVLNAFSQAPSTMQVSHSQVQE PGGVPQVFLTASSGTVQIPVSAVQL HQMAVIGQQAGSSSNLTELQVVNLD TAHSTKSETRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
