Recombinant Human STAT1 protein(Met1-Val712), His&GST-tagged
Cat.No. : | STAT1-7037H |
Product Overview : | Recombinant Human STAT1 (P42224-2) (Met 1-Val 712) was expressed in Insect Cells, fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
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Source : | Insect Cells |
Species : | Human |
Tag : | N-His&GST |
Protein length : | Met1-Val712 |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human STAT1/GST chimera consists of 950 amino acids and has a calculated molecular mass of 111 kDa. It migRates as an approximately 105 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 92 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | STAT1 signal transducer and activator of transcription 1, 91kDa [ Homo sapiens ] |
Official Symbol : | STAT1 |
Synonyms : | STAT1; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1-alpha/beta; ISGF 3; STAT91; transcription factor ISGF 3 components p91/p84; transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription-1; CANDF7; ISGF-3; DKFZp686B04100; |
Gene ID : | 6772 |
mRNA Refseq : | NM_007315 |
Protein Refseq : | NP_009330 |
MIM : | 600555 |
UniProt ID : | P42224 |
Products Types
◆ Recombinant Protein | ||
STAT1-01H | Recombinant Human STAT1 Protein, GST-tagged | +Inquiry |
STAT1-2741H | Recombinant Human STAT1 Protein, His-tagged | +Inquiry |
Stat1-6168M | Recombinant Mouse Stat1 Protein, Myc/DDK-tagged | +Inquiry |
STAT1-2901H | Recombinant Human STAT1 Protein, MYC/DDK-tagged | +Inquiry |
STAT1-4332R | Recombinant Rhesus Macaque STAT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
STAT1-555HCL | Recombinant Human STAT1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionSTAT1 is a signal transduction and transcriptional activator involved in regulating a variety of biological processes such as cell growth, differentiation, apoptosis, and immune response.
Mutations in the STAT1 gene have been found to be associated with a variety of diseases, including autoimmune diseases, primary immunodeficiency diseases, and malignant tumors.
The STAT1 protein is primarily activated by the JAK-STAT signaling pathway. When activated by the receptor, JAK kinase phosphorylates the STAT1 protein, allowing it to form dimers and enter the nucleus to regulate transcription of related genes.
The STAT1 protein plays an important role in many diseases, including tumors, immune-related diseases (such as immunodeficiency diseases, autoimmune diseases), infectious diseases (such as viral infections), etc.
Some activators or inhibitors of the STAT1 protein have been identified. These compounds can be used to study the function of the STAT1 protein and the development of disease treatments.
The STAT1 protein plays an important role in viral infection. It mediates interferon signaling, promotes antiviral immune responses, and inhibits viral replication and transmission.
Customer Reviews (3)
Write a reviewIt is well suited for our laboratory to induce specific immune responses.
It has great application potential and performs well in all aspects.
This protein has high yield and high purity, which greatly improves our production efficiency.
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