"STEAP3" Related Products

Recombinant Human STEAP3 protein, MYC/DDK-tagged

Cat.No.: STEAP3-16H
Product Overview: Recombinant Human STEAP3, transcript variant 3, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.
Source: HEK293
Species: Human
Tag: MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 54.4 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: STEAP3 STEAP family member 3, metalloreductase [ Homo sapiens ]
Official Symbol: STEAP3
Synonyms: STMP3; TSAP6; dudlin-2
Gene ID: 55240
mRNA Refseq: NM_001008410
Protein Refseq: NP_001008410
MIM: 609671
UniProt ID: Q658P3
Chromosome Location: 2q14.2
Pathway: Direct p53 effectors, organism-specific biosystem;Iron uptake and transport, organism-specific biosystem;Transferrin endocytosis and recycling, organism-specific biosystem;Transmembrane transport of small molecules, organism-specific biosystem;p53 signaling pathway, organism-specific biosystem;p53 signaling pathway, conserved biosystem;
Function: ferric-chelate reductase activity;metal ion binding;nucleotide binding;protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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