Recombinant Human STEAP4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: STEAP4-1556H
• Product Overview: STEAP4 MS Standard C13 and N15-labeled recombinant protein (NP_078912) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.8 kDa
• AA Sequence: MEKTCIDALPLTMNSSEKQETVCIF GTGDFGRSLGLKMLQCGYSVVFGSR NPQKTTLLPSGAEVLSYSEAAKKSD IIIIAIHREHYDFLTELTEVLNGKI LVDISNNLKINQYPESNAEYLAHLV PGAHVVKAFNTISAWALQSGALDAS RQVFVCGNDSKAKQRVMDIVRNLGL TPMDQGSLMAAKEIEKYPLQLFPMW RFPFYLSAVLCVFLFFYCVIRDVIY PYVYEKKDNTFRMAISIPNRIFPIT ALTLLALVYLPGVIAAILQLYRGTK YRRFPDWLDHWMLCRKQLGLVALGF AFLHVLYTLVIPIRYYVRWRLGNLT VTQAILKKENPFSTSSAWLSDSYVA LGILGFFLFVLLGITSLPSVSNAVN WREFRFVQSKLGYLTLILCTAHTLV YGGKRFLSPSNLRWYLPAAYVLGLI IPCTVLVIKFVLIMPCVDNTLTRIR QGWERNSKHTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: STEAP4 STEAP family member 4 [ Homo sapiens (human) ]
• Official Symbol: STEAP4
• Synonyms: STEAP4; STEAP family member 4; TNFAIP9, tumor necrosis factor, alpha induced protein 9; metalloreductase STEAP4; FLJ23153; STAMP2; TIARP; six transmembrane prostate protein 2; sixTransMembrane protein of prostate 2; tumor necrosis factor, alpha-induced protein 9; six-transmembrane epithelial antigen of prostate 4; tumor necrosis-alpha-induced adipose-related protein; TNFAIP9; DKFZp666D049
• Gene ID: 79689
• mRNA Refseq: NM_024636
• Protein Refseq: NP_078912
• MIM: 611098
• UniProt ID: Q687X5