Recombinant Human STING1 R232, K224R mutant Protein, His-tagged
Cat.No. : | STING1-149H |
Product Overview : | N-terminally Histidine-tagged human STING R232, K224R mutant purified from E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 28.8 kDa |
Protein length : | 138-379 (N-terminal truncation) |
Purity : | ≥70% estimated by SDS-PAGE |
Stability : | ≥ 1 year |
Storage : | At -80 centigrade. |
Storage Buffer : | 50 mM HEPES, pH 8.0, with 150 mM sodium chloride, and 10% glycerol |
Gene Name : | STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ] |
Official Symbol : | STING1 |
Synonyms : | STING1; stimulator of interferon response cGAMP interactor 1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173 |
Gene ID : | 340061 |
mRNA Refseq : | NM_198282 |
Protein Refseq : | NP_938023 |
MIM : | 612374 |
UniProt ID : | Q86WV6 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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