Recombinant Human STUB1 cell lysate

• Cat.No.: STUB1-1715HCL

Specification

• Description: STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008 [PubMed 18411298]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: STUB1
• Synonyms: STUB1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; STIP1 homology and U box containing protein 1; E3 ubiquitin-protein ligase CHIP; CHIP; HSPABP2; NY CO 7; SDCCAG7; UBOX1; antigen NY-CO-7; CLL-associated antigen KW-8; serologically defined colon cancer antigen 7; STIP1 homology and U box-containing protein 1; carboxy terminus of Hsp70-interacting protein; heat shock protein A binding protein 2 (c-terminal); NY-CO-7
• Gene ID: 10273
• mRNA Refseq: NM_005861
• Protein Refseq: NP_005852
• MIM: 607207
• UniProt ID: Q9UNE7
• Chromosome Location: 16p13.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem
• Function: Hsp70 protein binding; Hsp90 protein binding; SMAD binding; TPR domain binding; enzyme binding; kinase binding; ligase activity; misfolded protein binding; protein binding; protein binding, bridging; protein homodimerization activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-ubiquitin ligase activity