Recombinant Human SUMO1 Activating Enzyme Subunit 1
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Cat.No. : | SAE1-61H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human SAE1(aa1-347)produced in E. coli is a heterodimer that acts as the activatingenzyme for SUMO-1. |
Description : | Posttranslationalmodification of proteins by the addition of the small protein SUMO (seeSUMO1; MIM 601912), or sumoylation, regulates protein structure andintracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimerthat functions as a SUMO-activating enzyme for the sumoylation of proteins. |
Source : | E. coli |
Species : | Human |
Concentration : | 0.2mg/ml |
Formulation : | Liquid.In 50mM TRIS-HCl, pH 7.5, containing 1mM DTT and 200mM potassium chloride. |
Storage : | -80°C, LongTerm. |
OfficialSymbol : | SAE1 |
PDBrenderingbased on 1y8q. : |
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Gene Name : | SAE1 SUMO1 activating enzymesubunit 1 [ Homo sapiens ] |
Synonyms : | SAE1; SUMO1 activatingenzyme subunit 1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activatingenzyme subunit 1; SUMO-activating enzyme subunit 1; activator of SUMO1;sentrin/SUMO-activating protein AOS1; ubiquitin-like 1-activating enzyme E1A;ubiquitin-like protein SUMO-1 activating enzyme; AOS1; FLJ3091; HSPC140 |
Gene ID : | 10055 |
mRNA Refseq : | NM_001145713 |
Protein Refseq : | NP_001139185 |
MIM : | 613294 |
UniProt ID : | Q9UBE0 |
Chromosome Location : | 19q13.32 |
Pathway : | Ubiquitin mediated proteolysis |
Function : | ATP-dependent protein binding; contributes_to SUMO activatingenzyme activity; enzyme activator activity; ligase activity; protein heterodimerizationactivity; protein binding; ubiquitin activating enzyme activity |
◆ Recombinant Protein
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Sae1-5678M | Recombinant Mouse Sae1 Protein, Myc/DDK-tagged | +Inquiry |
SAE1-5223R | Recombinant Rat SAE1 Protein | +Inquiry |
SAE1-255H | Recombinant Human SAE1, GST-tagged | +Inquiry |
SAE1-508H | Recombinant Human SAE1, None tagged | +Inquiry |
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◆ Lysates
SAE1-001HCL | Recombinant Human SAE1 cell lysate | +Inquiry |
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