Recombinant Human SUMO1 Activating Enzyme Subunit 1

• Cat.No.: SAE1-61H
• Product Overview: Recombinant human SAE1(aa1-347)produced in E. coli is a heterodimer that acts as the activatingenzyme for SUMO-1.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-347 a.a.
• Description: Posttranslationalmodification of proteins by the addition of the small protein SUMO (seeSUMO1; MIM 601912), or sumoylation, regulates protein structure andintracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimerthat functions as a SUMO-activating enzyme for the sumoylation of proteins.
• Concentration: 0.2mg/ml
• Formulation: Liquid.In 50mM TRIS-HCl, pH 7.5, containing 1mM DTT and 200mM potassium chloride.
• Storage: -80°C, LongTerm.
• OfficialSymbol: SAE1

Gene Information

• Gene Name: SAE1 SUMO1 activating enzymesubunit 1 [ Homo sapiens ]
• Synonyms: SAE1; SUMO1 activatingenzyme subunit 1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activatingenzyme subunit 1; SUMO-activating enzyme subunit 1; activator of SUMO1;sentrin/SUMO-activating protein AOS1; ubiquitin-like 1-activating enzyme E1A;ubiquitin-like protein SUMO-1 activating enzyme; AOS1; FLJ3091; HSPC140
• Gene ID: 10055
• mRNA Refseq: NM_001145713
• Protein Refseq: NP_001139185
• MIM: 613294
• UniProt ID: Q9UBE0
• Chromosome Location: 19q13.32
• Pathway: Ubiquitin mediated proteolysis
• Function: ATP-dependent protein binding; contributes_to SUMO activatingenzyme activity; enzyme activator activity; ligase activity; protein heterodimerizationactivity; protein binding; ubiquitin activating enzyme activity