Recombinant Human SUMO1 Activating Enzyme Subunit 1 SAE1-61H

Recombinant Human SUMO1 Activating Enzyme Subunit 1


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Cat.No. : SAE1-61H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human SAE1(aa1-347)produced in E. coli is a heterodimer that acts as the activatingenzyme for SUMO-1.
Description : Posttranslationalmodification of proteins by the addition of the small protein SUMO (seeSUMO1; MIM 601912), or sumoylation, regulates protein structure andintracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimerthat functions as a SUMO-activating enzyme for the sumoylation of proteins.
Source : E. coli
Species : Human
Concentration : 0.2mg/ml
Formulation : Liquid.In 50mM TRIS-HCl, pH 7.5, containing 1mM DTT and 200mM potassium chloride.
Storage : -80°C, LongTerm.
OfficialSymbol : SAE1
PDBrenderingbased on 1y8q. :

Gene Name : SAE1 SUMO1 activating enzymesubunit 1 [ Homo sapiens ]
Synonyms : SAE1; SUMO1 activatingenzyme subunit 1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activatingenzyme subunit 1; SUMO-activating enzyme subunit 1; activator of SUMO1;sentrin/SUMO-activating protein AOS1; ubiquitin-like 1-activating enzyme E1A;ubiquitin-like protein SUMO-1 activating enzyme; AOS1; FLJ3091; HSPC140
Gene ID : 10055
mRNA Refseq : NM_001145713
Protein Refseq : NP_001139185
MIM : 613294
UniProt ID : Q9UBE0
Chromosome Location : 19q13.32
Pathway : Ubiquitin mediated proteolysis
Function : ATP-dependent protein binding; contributes_to SUMO activatingenzyme activity; enzyme activator activity; ligase activity; protein heterodimerizationactivity; protein binding; ubiquitin activating enzyme activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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