Description : |
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
71.9 kDa |
AA Sequence : |
MASSGMADSANHLPFFFGNITREEA EDYLVQGGMSDGLYLLRQSRNYLGG FALSVAHGRKAHHYTIERELNGTYA IAGGRTHASPADLCHYHSQESDGLV CLLKKPFNRPQGVQPKTGPFEDLKE NLIREYVKQTWNLQGQALEQAIISQ KPQLEKLIATTAHEKMPWFHGKISR EESEQIVLIGSKTNGKFLIRARDNN GSYALCLLHEGKVLHYRIDKDKTGK LSIPEGKKFDTLWQLVEHYSYKADG LLRVLTVPCQKIGTQGNVNFGGRPQ LPGSHPATWSAGGIISRIKSYSFPK PGHRKSSPAQGNRQESTVSFNPYEP ELAPWAADKGPQREALPMDTEVYES PYADPEEIRPKEVYLDRKLLTLEDK ELGSGNFGTVKKGYYQMKKVVKTVA VKILKNEANDPALKDELLAEANVMQ QLDNPYIVRMIGICEAESWMLVMEM AELGPLNKYLQQNRHVKDKNIIELV HQVSMGMKYLEESNFVHRDLAARNV LLVTQHYAKISDFGLSKALRADENY YKAQTHGKWPVKWYAPECINYYKFS SKSDVWSFGVLMWEAFSYGQKPYRG MKGSEVTAMLEKGERMGCPAGCPRE MYDLMNLCWTYDVENRPGFAAVELR LRNYYYDVVNTRTRPLEQKLISEED LAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |