Recombinant Human SYT2 protein, MYC/DDK-tagged

• Cat.No.: SYT2-35H
• Product Overview: Recombinant Human SYT2, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 46.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SYT2 synaptotagmin II [ Homo sapiens ]
• Official Symbol: SYT2
• Synonyms: SYT2; synaptotagmin II; synaptotagmin-2; synaptotagmin 2; SytII; FLJ42519
• Gene ID: 127833
• mRNA Refseq: NM_001136504
• Protein Refseq: NP_001129976
• MIM: 600104
• UniProt ID: Q8N9I0
• Chromosome Location: 1q32.1
• Pathway: Botulinum neurotoxicity, organism-specific biosystem; Disease, organism-specific biosystem; Neuronal System, organism-specific biosystem; Translocation of BoNT Light chain, organism-specific biosystem
• Function: metal ion binding; protein binding; transporter activity