| Description : |
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.4 kDa |
| AA Sequence : |
MFRTAVMMAASLALTGAVVAHAYYL KHQFYPTVVYLTKSSPSMAVLYIQA FVLVFLLGKVMGKVFFGQLRAAEME HLLERSWYAVTETCLAFTVFRDDFS PRFVALFTLLLFLKCFHWLAEDRVD FMERSPNISWLFHCRIVSLMFLLGI LDFLFVSHAYHSILTRGASVQLVFG FEYAILMTMVLTIFIKYVLHSVDLQ SENPWDNKAVYMLYTELFTGFIKVL LYMAFMTIMIKVHTFPLFAIRPMYL AMRQFKKAVTDAIMSRRAIRNMNTL YPDATPEELQAMDNVCIICREEMVT GAKRLPCNHIFHTSCLRSWFQRQQT CPTCRMDVLRASLPAQSPPPPEPAD QGPPPAPHPPPLLPQPPNFPQGLLP PFPPGMFPLWPPMGPFPPVPPPPSS GEAVAPPSTSAAALSRPSGAATTTA AGTSATAASATASGPGSGSAPEAGP APGFPFPPPWMGMPLPPPFAFPPMP VPPAGFAGLTPEELRALEGHERQHL EARLQSLRNIHTLLDAAMLQINQYL TVLASLGPPRPATSVNSTEETATTV VAAASSTSIPSSEATTPTPGASPPA PEMERPPAPESVGTEEMPEDGEPDA AELRRRRLQKLESPVAHTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
