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Recombinant Human TAPBP Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : TAPBP-154H
Product Overview : TAPBP MS Standard C13 and N15-labeled recombinant protein (NP_003181) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 47.63 kDa
AA Sequence : MKSLSLLLAVALGLATAVSAGPAVI ECWFVEDASGKGLAKRPGALLLRQG PGEPPPRPDLDPELYLSVHDPAGAL QAAFRRYPRGAPAPHCEMSRFVPLP ASAKWASGLTPAQNCPRALDGAWLM VSISSPVLSLSSLLRPQPEPQQEPV LITMATVVLTVLTHTPAPRVRLGQD ALLDLSFAYMPPTSEAASSLAPGPP PFGLEWRRQHLGKGHLLLAATPGLN GQMPAAQEGAVAFAAWDDDEPWGPW TGNGTFWLPRVQPFQEGTYLATIHL PYLQGQVTLELAVYKPPKVSLMPAT LARAAPGEAPPELLCLVSHFYPSGG LEVEWELRGGPGGRSQKAEGQRWLS ALRHHSDGSVSLSGHLQPPPVTTEQ HGARYACRIHHPSLPASGRSAEVTL EVAGLSGPSLEDSVGLFLSAFLLLG LFKALGWAAVYLSTCKDSKKKAETR TRPLEQKLISEEDLAANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : TAPBP TAP binding protein [ Homo sapiens (human) ]
Official Symbol : TAPBP
Synonyms : TAPBP; TAP binding protein; NGS17; TAPA; TPN; TPSN; tapasin; NGS-17; TAP binding protein (tapasin); TAP-associated protein
Gene ID : 6892
mRNA Refseq : NM_003190
Protein Refseq : NP_003181
MIM : 601962
UniProt ID : O15533

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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