Recombinant Human TBK1 Protein TBK1-010H

Recombinant Human TBK1 Protein

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Recombinant Human TBK1 Protein

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Cat.No. : TBK1-010H
Product Overview : Recombinant full length human TBK1 protein (1-729) without tag was expressed in insect cells (baculovirus).
Description : The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
Source : Insect cells
Species : Human
Form : 50 mM HEPES, pH 8.0, with 150 mM sodium chloride, and 10% glycerol
Bio-activity : ATPase activity confirmed by ADP detection assay
Molecular Mass : 84 kDa
Protein length : 1-729
Purity : ≥50% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
Shipping : Dry ice in continental US; may vary elsewhere
SDS-PAGE analysis of TBK1. :

Lane 1: MW Markers
Lane 2: TBK1 (2 µg)
Lane 3: TBK1 (4 µg)

ATPase Activity of TBK1 :

Gene Name : TBK1 TANK binding kinase 1 [ Homo sapiens (human) ]
Official Symbol : TBK1
Synonyms : TBK1; TANK binding kinase 1; NAK; T2K; IIAE8; FTDALS4; serine/threonine-protein kinase TBK1; NF-kB-activating kinase; NF-kappa-B-activating kinase; EC 2.7.11.1
Gene ID : 29110
mRNA Refseq : NM_013254
Protein Refseq : NP_037386
MIM : 604834
UniProt ID : Q9UHD2

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