Recombinant Human TCN2 Protein, His-tagged

• Cat.No.: TCN2-570H
• Product Overview: Recombinant Human TCN2(Glu19~Trp427) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 49.3kDa
• Protein length: Glu19~Trp427
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 92%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: TCN2 transcobalamin II [ Homo sapiens ]
• Official Symbol: TCN2
• Synonyms: TCN2; transcobalamin II; transcobalamin II; macrocytic anemia; transcobalamin-2; D22S676; D22S750; macrocytic anemia; TC2; vitamin B12-binding protein 2; II; TC; TC-2; TCII; TC II
• Gene ID: 6948
• mRNA Refseq: NM_000355
• Protein Refseq: NP_000346
• MIM: 613441
• UniProt ID: P20062