Recombinant Human TGFB1-Induced Anti-Apoptotic Factor 1, His-tagged

• Cat.No.: TIAF1-7137H
• Product Overview: Recombinant human TIAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 16.6 kDa.

Specification

• Description: TGFB1-induced anti-apoptotic factor 1, also known as TIAF1, inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. This protein involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
• Molecular Mass: 16.6 kDa (152aa)
• Protein length: 1-115aa
• AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TIAF1 TGFB1-induced anti-apoptotic factor 1 [ Homo sapiens ]
• Official Symbol: TIAF1
• Synonyms: TIAF1; TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; molecule associated with Jak-3 N-terminal; 12 kDa TGF-beta-1-induced antiapoptotic factor; MAJN; SPR210
• Gene ID: 9220
• mRNA Refseq: NM_004740
• Protein Refseq: NP_004731
• MIM: 609517
• UniProt ID: O95411
• Chromosome Location: 17q11.2
• Function: molecular_function