Recombinant Human TGFB1 Protein

• Cat.No.: TGFB1-226H
• Product Overview: Recombinant Mouse Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.

Specification

• Species: Mouse
• Source: Human Cells
• Protein Length: 279-390 a.a.
• Description: Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
• Form: Lyophilized from a 0.2 um filtered solution of 50mM Glycine, 150mM NaCl, pH 2.5.
• AA Sequence: Ala279-Ser390
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: TGFB1 transforming growth factor beta 1 [ Homo sapiens (human) ]
• Official Symbol: TGFB1
• Synonyms: TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; LAP; IBDIMDE; TGFbeta; TGF-beta1
• Gene ID: 7040
• mRNA Refseq: NM_000660.7
• Protein Refseq: NP_000651.3
• MIM: 190180
• UniProt ID: P04202