"TGFB1" Related Products

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Recombinant Human TGFB1 Protein, MYC/DDK-tagged

Cat.No.: TGFB1-706H
Product Overview: Recombinant human TGFB1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016].
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass: 28.4 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: transforming growth factor beta 1[ Homo sapiens ]
Official Symbol: TGFB1
Synonyms: CED; DPD1; LAP; TGFB; TGFbeta
Gene ID: 7040
mRNA Refseq: NM_000660.6
Protein Refseq: NP_000651.3
UniProt ID: P01137

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