Expand| Cat.No. : | TGFBR1-701H |
| Product Overview : | Recombinant human TGFBR1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
| Description : | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
| Source : | HEK293 |
| Species : | Human |
| Tag : | MYC/DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : | 53.6 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name : | transforming growth factor beta receptor 1[ Homo sapiens ] |
| Official Symbol : | TGFBR1 |
| Synonyms : | AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TGFR-1 |
| Gene ID : | 7046 |
| mRNA Refseq : | NM_004612.2 |
| Protein Refseq : | NP_004603.1 |
| MIM : | 190181 |
| UniProt ID : | P36897 |
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