|Product Overview :
||Recombinant human TGFBR1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
||The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
|Molecular Mass :
||> 80% as determined by SDS-PAGE and Coomassie blue staining
||>50 ug/mL as determined by microplate BCA method